Stage 2 of the 2023 Vuelta España Femenina was a lumpy stage that took place on .

The stage started in Orihuela and finished in Pilar de la Horadada, starting at with an expected finish at (average speed of 40 km/h).

The total distance of the stage was 106.8 km. The stage included 0 categorized climb(s) and 0 intermediate sprint(s), and had a total elevation gain of 1045 m, and a total descent of -1033 m.